TY - JOUR
T1 - Development of a biotic ligand model (BLM) predicting nickel toxicity to barley (Hordeum vulgare)
AU - Lock, Koen
AU - Van Eeckhout, Hilde
AU - De Schamphelaere, K. A. C
AU - Criel, P
AU - Janssen, C. R
N1 - Publication Authorstring : Lock, K.; Van Eeckhout, H.; De Schamphelaere, K.A.C.; Criel, P.; Janssen, C.R.
Publication RefStringPartII : <i>Chemosphere 66(7)</i>: 1346-1352
PY - 2007
Y1 - 2007
N2 - A biotic ligand model (BLM) was developed to predict nickel toxicity, affecting root growth of barley (Hordeum vulgare), in nutrient solutions. The extent to which Ca2+, Mg2+, Na+, K+ ions and pH each influenced nickel toxicity was determined. Higher activities of Mg2+ linearly increased the 4 d EC50Nl2+, while Ca2+, Na+, K+ and H+ activities did not significantly influence Ni2+ toxicity. Stability constants for the binding of Ni2+ and Mg2+ to the biotic ligand were obtained: log KNiBL = 5.27 and log KMgBL = 3.47. Further, it was calculated that on average 57% of the biotic ligand sites needed to be occupied by nickel to induce 50% root growth inhibition. Auto-validation of the BLM indicated that predicted EC50s differed from the observed EC50s by a factor of less than 2, indicating that the BLM concept may also be used to predict metal toxicity to terrestrial plants.
AB - A biotic ligand model (BLM) was developed to predict nickel toxicity, affecting root growth of barley (Hordeum vulgare), in nutrient solutions. The extent to which Ca2+, Mg2+, Na+, K+ ions and pH each influenced nickel toxicity was determined. Higher activities of Mg2+ linearly increased the 4 d EC50Nl2+, while Ca2+, Na+, K+ and H+ activities did not significantly influence Ni2+ toxicity. Stability constants for the binding of Ni2+ and Mg2+ to the biotic ligand were obtained: log KNiBL = 5.27 and log KMgBL = 3.47. Further, it was calculated that on average 57% of the biotic ligand sites needed to be occupied by nickel to induce 50% root growth inhibition. Auto-validation of the BLM indicated that predicted EC50s differed from the observed EC50s by a factor of less than 2, indicating that the BLM concept may also be used to predict metal toxicity to terrestrial plants.
U2 - 10.1016/j.chemosphere.2006.07.008
DO - 10.1016/j.chemosphere.2006.07.008
M3 - A1: Web of Science-article
VL - 66
SP - 1346
EP - 1352
JO - Chemosphere
JF - Chemosphere
SN - 0045-6535
IS - 7
ER -