The rise and fall of the ancient northern pike master sex-determining gene

Qiaowei Pan; Romain Feron; Elodie Jouanno; Hugo Darras; Amaury Herpin; Ben Koop; Eric Rondeau; Frederick W Goetz; Wesley A Larson; Louis Bernatchez; Mike Tringali; Stephen S Curran; Eric Saillant; Gael PJ Denys; Frank A von Hippel; Songlin Chen; J Andrés López; Hugo Verreycken; Konrad Ocalewicz; Rene Guyomard; Camille Eche; Jerome Lluch; Celine Roques; Hongxia Hu; Roger Tabor; Patrick DeHaan; Krista M Nichols; Laurent Journot; Hugues Parrinello; Christophe Klopp; Elena A Interesova; Vladimir Trifonov; Manfred Schartl; John Postlethwait; Yann Guiguen; Molly Przeworski; Detlef Weigel

doi:10.7554/eLife.62858

The rise and fall of the ancient northern pike master sex-determining gene

Qiaowei Pan
, Romain Feron
, Elodie Jouanno
, Hugo Darras
, Amaury Herpin
, Ben Koop
, Eric Rondeau
, Frederick W Goetz
, Wesley A Larson
, Louis Bernatchez
, Mike Tringali
, Stephen S Curran
, Eric Saillant
, Gael PJ Denys
, Frank A von Hippel
, Songlin Chen
, J Andrés López
, Hugo Verreycken
, Konrad Ocalewicz
, Rene Guyomard

Camille Eche, Jerome Lluch, Celine Roques, Hongxia Hu, Roger Tabor, Patrick DeHaan, Krista M Nichols, Laurent Journot, Hugues Parrinello, Christophe Klopp, Elena A Interesova, Vladimir Trifonov, Manfred Schartl, John Postlethwait, Yann Guiguen, Molly Przeworski (Editor), Detlef Weigel (Editor)

Monitoring and Restoration of Aquatic Fauna

Research output: Contribution to journal › A1: Web of Science-article › peer-review

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Abstract

The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determination in an entire teleost order (Esociformes). We discovered that the northern pike (Esox lucius) master sex-determining gene originated from a 65 to 90 million-year-old gene duplication event and that it remained sex linked on undifferentiated sex chromosomes for at least 56 million years in multiple species. We identified several independent species- or population-specific sex determination transitions, including a recent loss of a Y chromosome. These findings highlight the diversity of evolutionary fates of master sex-determining genes and the importance of population demographic history in sex determination studies. We hypothesize that occasional sex reversals and genetic bottlenecks provide a non-adaptive explanation for sex determination transitions.

Original language	English
Journal	eLife
Volume	10
Pages (from-to)	e62858
ISSN	2050-084X
DOIs	https://doi.org/10.7554/eLife.62858
Publication status	Published - 28-Jan-2021

Thematic List 2020

Water
Other

Taxonomic list

bony fishes (Osteichtyes)

Geographic list

Europe
New World (North, Central and South America)

Technological

genetic technologies

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10.7554/eLife.62858Licence: CC BY

Pan_etal_2021_eLifeFinal published version, 7.13 MBLicence: CC BY

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Pan, Q., Feron, R., Jouanno, E., Darras, H., Herpin, A., Koop, B., Rondeau, E., Goetz, F. W., Larson, W. A., Bernatchez, L., Tringali, M., Curran, S. S., Saillant, E., Denys, G. PJ., von Hippel, F. A., Chen, S., López, J. A., Verreycken, H., Ocalewicz, K., ... Weigel, D. (Ed.) (2021). The rise and fall of the ancient northern pike master sex-determining gene. eLife, 10, e62858. https://doi.org/10.7554/eLife.62858

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title = "The rise and fall of the ancient northern pike master sex-determining gene",

abstract = "The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determination in an entire teleost order (Esociformes). We discovered that the northern pike (Esox lucius) master sex-determining gene originated from a 65 to 90 million-year-old gene duplication event and that it remained sex linked on undifferentiated sex chromosomes for at least 56 million years in multiple species. We identified several independent species- or population-specific sex determination transitions, including a recent loss of a Y chromosome. These findings highlight the diversity of evolutionary fates of master sex-determining genes and the importance of population demographic history in sex determination studies. We hypothesize that occasional sex reversals and genetic bottlenecks provide a non-adaptive explanation for sex determination transitions.",

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year = "2021",

month = jan,

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Pan, Q, Feron, R, Jouanno, E, Darras, H, Herpin, A, Koop, B, Rondeau, E, Goetz, FW, Larson, WA, Bernatchez, L, Tringali, M, Curran, SS, Saillant, E, Denys, GPJ, von Hippel, FA, Chen, S, López, JA, Verreycken, H, Ocalewicz, K, Guyomard, R, Eche, C, Lluch, J, Roques, C, Hu, H, Tabor, R, DeHaan, P, Nichols, KM, Journot, L, Parrinello, H, Klopp, C, Interesova, EA, Trifonov, V, Schartl, M, Postlethwait, J, Guiguen, Y, Przeworski, M (ed.) & Weigel, D (ed.) 2021, 'The rise and fall of the ancient northern pike master sex-determining gene', eLife, vol. 10, pp. e62858. https://doi.org/10.7554/eLife.62858

TY - JOUR

T1 - The rise and fall of the ancient northern pike master sex-determining gene

AU - Pan, Qiaowei

AU - Feron, Romain

AU - Jouanno, Elodie

AU - Darras, Hugo

AU - Herpin, Amaury

AU - Koop, Ben

AU - Rondeau, Eric

AU - Goetz, Frederick W

AU - Larson, Wesley A

AU - Bernatchez, Louis

AU - Tringali, Mike

AU - Curran, Stephen S

AU - Saillant, Eric

AU - Denys, Gael PJ

AU - von Hippel, Frank A

AU - Chen, Songlin

AU - López, J Andrés

AU - Verreycken, Hugo

AU - Ocalewicz, Konrad

AU - Guyomard, Rene

AU - Eche, Camille

AU - Lluch, Jerome

AU - Roques, Celine

AU - Hu, Hongxia

AU - Tabor, Roger

AU - DeHaan, Patrick

AU - Nichols, Krista M

AU - Journot, Laurent

AU - Parrinello, Hugues

AU - Klopp, Christophe

AU - Interesova, Elena A

AU - Trifonov, Vladimir

AU - Schartl, Manfred

AU - Postlethwait, John

AU - Guiguen, Yann

A2 - Przeworski, Molly

A2 - Weigel, Detlef

PY - 2021/1/28

Y1 - 2021/1/28

N2 - The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determination in an entire teleost order (Esociformes). We discovered that the northern pike (Esox lucius) master sex-determining gene originated from a 65 to 90 million-year-old gene duplication event and that it remained sex linked on undifferentiated sex chromosomes for at least 56 million years in multiple species. We identified several independent species- or population-specific sex determination transitions, including a recent loss of a Y chromosome. These findings highlight the diversity of evolutionary fates of master sex-determining genes and the importance of population demographic history in sex determination studies. We hypothesize that occasional sex reversals and genetic bottlenecks provide a non-adaptive explanation for sex determination transitions.

AB - The understanding of the evolution of variable sex determination mechanisms across taxa requires comparative studies among closely related species. Following the fate of a known master sex-determining gene, we traced the evolution of sex determination in an entire teleost order (Esociformes). We discovered that the northern pike (Esox lucius) master sex-determining gene originated from a 65 to 90 million-year-old gene duplication event and that it remained sex linked on undifferentiated sex chromosomes for at least 56 million years in multiple species. We identified several independent species- or population-specific sex determination transitions, including a recent loss of a Y chromosome. These findings highlight the diversity of evolutionary fates of master sex-determining genes and the importance of population demographic history in sex determination studies. We hypothesize that occasional sex reversals and genetic bottlenecks provide a non-adaptive explanation for sex determination transitions.

U2 - 10.7554/eLife.62858

DO - 10.7554/eLife.62858

M3 - A1: Web of Science-article

SN - 2050-084X

VL - 10

SP - e62858

JO - eLife

JF - eLife

ER -

The rise and fall of the ancient northern pike master sex-determining gene

Abstract

Thematic List 2020

Taxonomic list

Geographic list

Technological

Access to Document

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Cite this