Research output

Development of a biotic ligand model (BLM) predicting nickel toxicity to barley (Hordeum vulgare)

Research output: Contribution to journalA1: Web of Science-article



Original languageEnglish
Issue number7
Pages (from-to)1346-1352
Number of pages7
Publication statusPublished - 2007


A biotic ligand model (BLM) was developed to predict nickel toxicity, affecting root growth of barley (Hordeum vulgare), in nutrient solutions. The extent to which Ca2+, Mg2+, Na+, K+ ions and pH each influenced nickel toxicity was determined. Higher activities of Mg2+ linearly increased the 4 d EC50Nl2+, while Ca2+, Na+, K+ and H+ activities did not significantly influence Ni2+ toxicity. Stability constants for the binding of Ni2+ and Mg2+ to the biotic ligand were obtained: log KNiBL = 5.27 and log KMgBL = 3.47. Further, it was calculated that on average 57% of the biotic ligand sites needed to be occupied by nickel to induce 50% root growth inhibition. Auto-validation of the BLM indicated that predicted EC50s differed from the observed EC50s by a factor of less than 2, indicating that the BLM concept may also be used to predict metal toxicity to terrestrial plants.
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  • Lock_etal_2007_Chemosphere

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